One of the main goals of proteomics is to unravel the many modifications important for biological activity. Post-translational modifications (PTMs) extend the range of protein function by attaching it ...

The amino acid side chains of proteins undergo various post-translational modifications (PTMs) which significantly impact protein function and mediate complex cellular events. Measuring the dynamics, ...

The focus of vertebrate studies has mainly been on canonical phosphorylation, but research indicates that phosphorylation of other non-canonical amino acids also regulates integral aspects of cell ...

image: An engineered protein nanopore directed a water flux strong enough to capture, unfold and translocate proteins exceeding 1200 amino acids in length. Modulation of electrical current during ...

Tsukuba, Japan—Proteins are subject to post-translational chemical modifications that result in functional diversity. Methylation is one such modification that is generally believed to occur on lysine ...

A new statistical model demonstrates the ability to correctly predict the folding mechanisms for both small and large proteins. The function of a protein is determined by its structure. From the rigid ...