Dormant cancer cells can change shape to survive immune system attack

Cancer cells that have broken away from a primary tumor can lurk in the body for years in a dormant state, evading immune ...
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Centromere protein I, a cell cycle checkpoint gene, accelerates tumor progression via the hippo pathway and mediates immune escape in hepatocellular carcinoma

Cell cycle checkpoint-related genes (CCCRGs) are implicated in the development and progression of hepatocellular carcinoma ...
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Why some cells are more susceptible to cancer

The ability of mutations to cause cancer depends on how fast they force cells to divide, Sinai Health researchers have found. The study, led by Dr. Rod Bremner, a Senior Investigator at the ...

This cancer is stubborn, but new drug regimen shows promise

An immunotherapy kept multiple myeloma at bay for over 80 percent of patients in a three-year clinical trial, and the FDA ...

New vulnerability identified in aggressive breast cancer

Researchers at University of California San Diego have identified a previously unrecognized treatment target for ...
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Critical Coordinator of DNA Repair During Cell Division Identified

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...
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Study identifies PUF60 as a critical vulnerability in triple negative breast cancer

Researchers at University of California San Diego have identified a previously unrecognized treatment target for ...