A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency partially depends on the usage of a codon, or sequence of three nucleotides, that ...

This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).

A research team has developed DeepCodon, a deep learning–based codon optimization tool that significantly improves heterologous protein expression in Escherichia coli while preserving functionally ...

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency partially depends ...

A new study finds that at least one Archaea has surprisingly flexibility when interpreting genetic code, which goes against a ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, No. 26 (Jun. 26, 2007), pp. 10824-10829 (6 pages) In universal-code eukaryotes, a single-translation ...

DNA has often been called “the book of life,” but this popular phrase makes some biologists squirm a bit. True, DNA bears our genes, which spell out the instructions our cells use to make ...

Two sets of ribosome structures have recently led to two different interpretations of what limits the accuracy of codon translation by transfer RNAs. In this review, inspired by this intermezzo at the ...