This is a preview. Log in through your library . Abstract We consider a general class of varying coefficient mixed models where random effects are introduced to account for between-subject variation.

Estimating equations are used to develop simple non-iterative estimates of the κ-coefficient that can be used when there are more than two random raters and/or unbalanced data (each subject is not ...

This section covers Twin and SNP heritability, h2 from whole genome sequencing, non-additive genetic effects and GWAS approaches. To better compare and understand the different approaches and models ...

We continue the exploration of the statistical landscape, including polygenic risk scores (calculation and evaluation), longitudinal models, to conclude on how Statistical Equation Modeling (SEM) can ...