Colchicine use is associated with a modest reduction in the long-term risk for total joint arthroplasty (TJA) among individuals with gout, according to study findings published in Arthritis & ...

BASEL, Switzerland—Low-dose colchicine doesn’t significantly reduce MACE in patients who have had a nonsevere ischemic stroke or high-risk TIA, according to the results of the CONVINCE trial. Through ...

Colchicine may be used with caution to manage flare-ups of crystal-induced arthritis among patients with severe chronic kidney disease, with dosage modifications and careful monitoring required.

NEW YORK — New insights into colchicine's disruption of the pathway that contributes to arterial inflammation and new clinical studies of the drug could pave the way toward greater use of the ...

WASHINGTON, DC – OCTOBER 29, 2024 – The largest trial to examine the impact of colchicine in acute myocardial infarction (MI) found that both acute and long-term colchicine use did not reduce ...

(Boston)—Gout is the most common form of inflammatory arthritis, with worldwide prevalence of approximately four%. The accumulation of monosodium urate crystals in gout leads to the clinical ...

Depending on one’s perspective, the anti-inflammatory colchicine is either an unsung and underprescribed drug for patients with cardiovascular disease, or it’s an agent with limited clinical benefit ...

WASHINGTON — Colchicine does not protect against major cardiovascular adverse events after an acute myocardial infarction, according to a multinational placebo-controlled trial of more than 7000 ...

Acetaminophen use, which was allowed as needed, was not taken less often by patients assigned to colchicine. (HealthDay News) — Colchicine fails to improve knee pain, function, or size of synovial ...

A recent review found that low dose colchicine may help prevent heart attacks and strokes in individuals who already have cardiovascular disease. The review also found that colchicine likely doesn’t ...

The colchicine-binding domain (CBD) of tubulin, one of the earliest identified regulatory sites, remains underexplored in oncology despite its proven success in other therapeutic areas. Drugs ...

DEAR DR. ROACH: I'm a 78-year-old man with a stent and a blockage in one of the arteries to my heart. I am on a low-fat diet and take ramipril for cholesterol. My levels are very good (total ...