Researchers explored a novel strategy involving CRISPR–Cas3 and investigated its potential using a mouse model of ...

A new CRISPR breakthrough shows scientists can turn genes back on without cutting DNA, by removing chemical tags that act ...

CRISPR–Cas9-based therapies are widely investigated for their clinical applications. However, there are limitations ...

For decades, the dream of fixing harmful mutations in mitochondrial DNA felt out of reach. Scientists have long known these mutations cause serious diseases that pass down only through mothers. They ...

The CRISPR gene editing technique has had a dramatic influence on biomedical research, and has even been applied to a few humans to treat disease. Since its invention, scientists have improved, ...

Researchers have unveiled a way to flip genes back on without slicing into the genome, a shift that could make CRISPR far ...

As people grow older, their immune systems do not simply slow down, they often become locked into a simmering, ...

Gene editing is now reaching the mainstream, ushering in a new era of genetic manipulation. Traditionally, inserting or deleting entire genes, regulating their expression, and altering specific ...

The authors do not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and have disclosed no relevant affiliations beyond their ...