Use lower end of dosing 0. In heart failure, higher dosages have no additional benefit and may increase toxicity; decreased renal order lanoxin digoxin may lead to increased toxicity. Very narrow ...
In patients with heart failure with reduced ejection fraction (HFrEF) who have an implantable cardioverter-defibrillator (ICD), the use of digoxin may increase the risk of ventricular tachyarrhythmia ...