Obesity is a global epidemic and a major cause of morbidity and mortality because it increases the risk for comorbidities, ...

Drug molecules and biofuels can be made to order by living cell factories, where biological enzymes do the job. Now researchers at Chalmers University of Technology have developed a computer model ...

Coupled oxygen transfer and electron transfer reactions that use cofactors are enzymatic reactions of crucial significance to all lifeforms from bacteria to vertebrates. In the European Journal of ...

A naturally occurring human enzyme -called cyclophilin 40 or CyP40- can unravel protein aggregates that contribute to both Alzheimer's disease and Parkinson's disease, according to a study. The ...

Membrane-associated proteins play a vital role in a variety of cellular processes, yet little is known about the membrane-association mechanism. Lipoprotein-associated phospholipase A 2 (Lp-PLA 2) is ...

Mathematical modeling helps researchers to understand how enzymes in the body work to ensure normal functioning. The models also can show how genetic mutations alter the enzymes' behavior in ways that ...

A model of the genome is described which relates certain observations on the additive nature of enzyme activity to observations on the quantitative genetics of fitness traits. The model assumes that ...

The protein cytochrome c oxidase (CcO) is the ultimate enzyme responsible for all aerobic life on Earth, from bacteria to people. It is also a crucial component of the cellular machinery that ...

Human induced pluripotent stem cell (iPSC)-derived motor neurons (in green) co-cultured with iPSC-derived astrocytes (in red). [VIB] Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s ...