How major nuclear protein complexes control specialized gene regulation in cancer and beyond

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...
Nature

Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells

In contrast to most dendritic-cell populations, Langerhans cells repopulate locally throughout life in the steady state, independently of any input from the blood circulation. In contrast to quiescent ...
Nature

Intrahippocampal injection of a lentiviral vector expressing neurogranin enhances cognitive function in 5XFAD mice

Progressive cognitive declines are the main clinical symptoms of Alzheimer’s disease (AD). Cognitive impairment in AD is directly correlated with amyloid beta (Aβ)-mediated synaptic deficits. It is ...
News Medical

Study: Neurons expressing dopamine D2 receptors have different molecular features, functions

An international collaboration, which included the involvement of the research team from the Institut de Neurociències of the UAB (INC-UAB), has shown that neurons expressing dopamine D2 receptors ...