New research has uncovered a complex interplay between extracellular matrix (ECM) structure and the transcriptional responses of cancer cells, showing how they alter their gene expression to ‘escape’ ...

These fiber-producing cells, or fibroblasts, make collagen and the extracellular matrix that gives shape and structure to our tissues. Fibroblasts can be found in many solid tumors, but they are ...

Brazilian research shows that stellate pancreatic cells produce periostin, remodeling tissue and facilitating tumor infiltration, a key mechanism of the aggressiveness and high mortality of the ...

Engitix Ltd (“Engitix”), a biotech company targeting the extracellular matrix (ECM) to develop transformative therapies for cancer and fibrosis, today announced the closing of a $25 million Series A ...

All cells, from bacteria to mammalian cells, produce extracellular vesicles—tiny membrane-enclosed packages of bioactive cargo. 1 Until relatively recently, scientists believed these organic ...

Extracellular vesicles (EVs), including exosomes, microvesicles, apoptotic bodies, and many other EV subtypes, have emerged ...