Colorectal cancer is one of the main causes of cancer mortality in Western societies. Experimental, epidemiological and clinical evidence show that diets consumed by Western populations have an ...

Figure 1: Structure of FRα bound to folic acid. Figure 3: Folic acid affinities of FRα ligand-binding-pocket mutants. In summary, many cancers highly express FRα, which has therefore become an ...

Scientists finally have a structure for the folate receptor. The receptor plays a key role in cancer, and the work could lead to better ways to design anticancer medications. “The folate community has ...

Folic acid is the synthetic form of folate, which is a naturally occurring B vitamin. Manufacturers add folic acid to supplements and fortified foods because it helps produce red blood cells, among ...