It’s one of life’s most defining moments—that crucial step in embryonic development, when an indistinct ball of cells rearranges itself into the orderly three-layered structure that sets the stage for ...
Scientists revise the current textbook knowledge about gastrulation, the formation of the basic body plan during embryonic development. Their study in mice has implications for cell replacement ...
Gastrulation, a prerequisite for organogenesis, begins with the formation of the primitive streak (PS), where epiblast cells experience an epithelial-to-mesenchymal transition (EMT) to exit the ...
A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development. When the zygote, or the fertilised egg, starts to develop, ...
Animal development consists of a cascade of tissue differentiation and shape change. Associated mechanical signals regulate tissue differentiation. Here we demonstrate that endogenous mechanical cues ...
In their publication in Science, Professor Guojun Sheng (Kumamoto University, Japan), Professor Alfonso Martinez Arias (Universidad Pompeu Fabra, Spain) and Professor Ann Sutherland (University of ...
Alaniz Emig A, Williams MLK. Generation of Naïve Blastoderm Explants from Zebrafish Embryos. J Vis Exp. 2021 Jul 30;(173). doi: 10.3791/62797. PMID: 34398141. View article Williams ML, Solnica-Krezel ...
Gastrulation is the formation of the three principal germ layers - endoderm, mesoderm and ectoderm. Understanding the formation of the basic body plan is not only important to reveal how the ...
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