Labroots

Analytical Validation of a Next Generation Sequencing Laboratory-Developed Test

Next-generation sequencing (NGS) has become the go-to tool for testing laboratories looking for increased efficiencies and profitability. NGS allows labs to use smaller tissue samples and reduced time ...
Labroots

Analytical and Clinical Validation Requirements for Next Generation Sequencing Laboratory-Developed Tests

Next generation sequencing (NGS) has revolutionized molecular diagnostic testing. It is important to note that, as with many molecular diagnostic tests currently in clinical use, there are very few ...
ascopubs.org

Multi-clinical laboratory validation of a gene expression-based tissue of origin test applied to poorly differentiated and undifferentiated cancers

Outcome of patients with locally advanced breast cancer (LABC) followed at the University of Cincinnati (UC) No significant financial relationships to disclose. This is an ASCO Meeting Abstract from ...
Nature

Molecular genetic testing for ultra rare diseases: models for translation from the research laboratory to the CLIA-certified diagnostic laboratory

Clinical Laboratory Improvement Amendments (CLIA)-certified clinical molecular diagnostic laboratory—a molecular diagnostic laboratory that has obtained formal certification through CLIA, 1 under the ...