A new clinical practice update outlines a stepwise approach to diagnosing and managing refractory constipation before ...

Surgery for refractory constipation should be a last resort, used only after comprehensive physiologic and psychological ...

All standard over-the-counter and FDA-approved therapies for constipation should be trialed, followed by trials of off-label prescription agents ...

Over the past 20 years, the use of opiates and opioids for the management of chronic pain has significantly increased. Approximately 40% to 90% of patients treated with opioids experience ...