Tandem mass spectrometry is a powerful tool in proteomics. By ionizing peptides and then fragmenting those ions into smaller product ions, researchers can determine the biomolecules’ amino acid ...
Effective protein characterization depends on the precise isolation and fragmentation of peptide ions within the mass spectrometer, typically coupled with liquid chromatography (LC-MS/MS). In a ...
MALDI remains a powerful tool for analyzing large biomolecules with minimal fragmentation. In this process, peptides or proteins are co-crystallized with a matrix on a metal plate. A laser pulse ...
Electron ionization (EI) is a hard ionization method that is typically used with gas chromatography-mass spectrometry (GC-MS). The mass spectral fragmentation patterns generated by EI are used for ...
After three years of development, the National Institute of Standards and Technology (NIST) has released a major upgrade of the widely used NIST/EPA/NIH Mass Spectral Library. The library is an ...
This article highlights the ZenoTOF 8600 system's ability to detect, measure, and structurally describe bile acid levels in human plasma. Bile acid analysis in human samples has grown increasingly ...