In an age when the majority of monogenic human disease genes have been identified, one of the challenges for the coming generation of human geneticists will be to resolve complex polygenic and ...
Real-world adverse events are rarely monocausal. They emerge from the interaction of drug exposure, comorbid conditions, physiological states, concomitant medications, and patient-specific ...
Many common health conditions arise due to a combination of genetic factors and lifestyle-related behaviors. People’s understanding of the multifactorial nature of health conditions has implications ...
Correspondence to Dr Sally Hopewell, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK; sally.hopewell{at}csm.ox.ac.uk Objective ...
In some cases, more than one factor may be responsible for causing the birth defect. For example genes form both parents may interact with one another to produce an undesirable effect in the presence ...
Cardiovascular morbidity is a major burden in patients with type 2 diabetes. In the Steno-2 Study, we compared the effect of a targeted, intensified, multifactorial intervention with that of ...
Spina bifida is among the most common and debilitating neural tube defects, affecting approximately 1 in every 2,875 newborns in the United States. This congenital malformation disrupts the normal ...
To what extent can our intestinal microbiota predict the risk of developing diseases? In the case of multifactorial diseases, bacterial taxa alone do not provide much information, according to a study ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback