Axonal protein synthesis defect identified as potential early driver in ALS progression

Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production ...
News-Medical.Net on MSN

ALS breakthrough: Restoring protein production in motor neuron axons

Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production, a process that fails in amyotrophic lateral sclerosis (ALS).
C&EN

When protein translation fails, mechanical forces can determine how a protein gets completed

The cells in living organisms are constantly making proteins. Ribosomes, the RNA-protein complexes that make other proteins, ...

Uncovering how occludin protein maintains blood-brain and blood-retinal barriers

The blood-brain and blood-retinal barriers are protective systems that prevent harmful substances from entering the brain and ...

Boosting the cell's own cleanup: New class of small molecules accelerate natural protein degradation

Proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in ...
Purdue University

One Health: Control of protein folding strikes at the root of disease

WEST LAFAYETTE, Ind. — The shared culprit in a slew of diseases — cancers, neurodegenerative diseases, diabetes — is molecules our cells have made incorrectly. Think of them as proteins gone wrong.