Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...
The insulin receptor (IR) is a prototypical receptor tyrosine kinase that orchestrates critical cellular processes, including metabolism, cell growth and differentiation. Activation of the IR involves ...
Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...
In a recent study published by Nature Communications, researchers uncovered a previously unknown method by which androgen-activated androgen receptors (ARs) increase fucosyltransferase 4 (FUT4) ...
A team has demonstrated new mechanisms that are involved in the development of inflammatory cardiovascular diseases. A team led by LMU researchers Christian Weber and Yvonne Döring has demonstrated ...
A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled ...
A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely ...
Research led by the SickKids Research Institute in Toronto and the University of Pennsylvania, has found that immune-related ...
The histamine H3 receptor typically becomes active upon binding to one of its agonists, such as histamine itself. This, in ...
A vitamin A byproduct has been found to quietly disarm the immune system, allowing tumors to evade attack and weakening ...