To study how a key chemical neuromodulator affects signaling in the brain's cortex, Garrett Neske, PhD, has received a three-year, $300,000 grant from the Whitehall Foundation, a nonprofit ...

Both presenilin-1 or the less-studied presenilin-2 can act as the catalytic subunit of γ-secretase, the enzyme responsible for churning out Aβ peptides. A new study, published November 29 in Nature ...

A) Taste tissue of wild-type mice and taste cell synaptic dysfunction mice (SNAP-cKO). In SNAP-cKO mice, the number of sour-sensing cells is reduced. B) Gustatory nerve responses to various taste ...

Synaptic transmission is an energy hog. It requires neurons to tap ATP reserves to respond to incoming signals. How do they pull this off, thousands to millions of times per day? A new study ...

Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the ...

The tongue contains numerous taste buds-tiny sensory organs responsible for detecting taste. Taste buds consist of specialized cells that translate chemical stimuli into neural signals. Among them, ...