A sugar on mycobacteria binds to the immune receptor dectin-1 on host macrophages, helping the bacteria survive and driving ...

The goal of the study is to investigate host genetic and immunologic predictors of resistance to M. tuberculosis infection and progression from latent M. tuberculosis infection to active tuberculosis ...

A novel iPSC-derived lung-on-chip model mimics human alveolar tissue, revealing macrophage-driven tuberculosis responses.

A histone acetylome-wide associations study (HAWAS) performed in immune cells from patients with active Mycobacterium tuberculosis infection versus those from healthy controls, has for the first time ...

CHAPEL HILL -- New research led by a University of North Carolina at Chapel Hill scientist shows for the first time how Mycobacterium tuberculosis, the germ responsible for TB, uses a system for ...

New observations of the early stages of tuberculosis infection may turn scientists' understanding of the bug's pathogenesis on its head: clumps of immune cells, called granulomas, long thought to ...

Down-regulation of plasma exosome-derived apolipoproteins APOA1, APOB, and APOC1 indicates DR-TB status and lipid metabolism regulation in pathogenesis. Group case-controlled study assessed 17 drug ...

Disseminated tuberculosis is a type of tuberculosis (TB) where mycobacteria spread via blood to other organs beyond the lungs. It can cause severe multiple-organ damage in the absence of early ...