Conformational change of a biomolecule—a change in its structure—is the ultimate basis for signaling in biology. A convenient and direct way of detecting structural changes in protein targets, and one ...
Recently, the research team of Prof. WANG Qian from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) and Prof. BAI Fang from ShanghaiTech University ...
The way proteins move is often what gives them biological activity: they can open, close, twist, and rearrange themselves in ways that allow them to bind to other molecules or perform complex ...
In a recent Current Research in Structural Biology study, researchers demonstrate that the energy landscape of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibits significant ...
Cancer is one of the leading causes of death worldwide, affecting over 20 million individuals and killing 9.7 million in 2022 alone. Each of ~200 cancer types (and multiple subtypes) presents an ...
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