Molecular and cellular mechanisms of epithelial–mesenchymal transition (EMT), crucial in development and pathogenesis, are still poorly understood. Here we provide evidence that distinct cellular ...

Gastrulation is a process common to nearly all metazoan organisms during which an embryo with distinct tissue layers develops out of a seemingly unstructured assembly of cells referred to as 'blastula ...

Only two weeks after fertilization, the first sign of the formation of the 3 axes of the human body (head/tail, ventral/dorsal, and right/left) begins to appear. At this stage, known as gastrulation, ...

Scientists revise the current textbook knowledge about gastrulation, the formation of the basic body plan during embryonic development. Their study in mice has implications for cell replacement ...

How does the “body” take shape? The body of animals is highly complex, containing distinct regions that carry out specific functions. As the body forms during embryogenesis, three germ layers are ...

Gastrulation research reveals novel details about embryonic development Scientists from Helmholtz Zentrum München are revising the current textbook knowledge about gastrulation, the formation of the ...

Researchers offer a phylogenetic and ontogenetic overview of the primitive streak and its role in mediating amniote (vertebrate animals that develop on land) gastrulation, and discuss the implications ...

When the zygote, or the fertilised egg, starts to develop, the soon forming inner cell mass, a cluster of cells that will eventually develop into the individual, retains its pluripotent stem cell ...

Jusque-là sphérique, l'embryon s'invagine pour former une nouvelle cavité interne (en plus du blastocèle préexistant) : l'archentéron, futur tube digestif. À la fin de cette étape, la gastrula adopte ...

Scientists from Helmholtz Zentrum München revise the current textbook knowledge about gastrulation, the formation of the basic body plan during embryonic development. Their study in mice has ...

In their publication in Science, Professor Guojun Sheng (Kumamoto University, Japan), Professor Alfonso Martinez Arias (Universidad Pompeu Fabra, Spain) and Professor Ann Sutherland (University of ...