Peer-reviewed discovery platform and data in PNAS show that single transcription factor modulation reverses aging-associated gene expression and restores healthy cellular and tissue function in models ...

A team led by researchers has discovered that a group of cells located in the skin and other areas of the body, called neural crest stem cells, are the source of reprogrammed neurons found by other ...

Prof. Roger Pedersen, Stanford University, and Dr. Thomas Moreau, bit.bio, will give an overview of the innovative history and recent developments in transcription factor-mediated cellular ...

The capacity of an organism to regenerate depends on cell dedifferentiation followed by proliferation. Mammals, in general, have limited regenerative capacity. Now, a team of researchers at the Salk ...

Scientists have observed signs of rejuvenation in the pancreas, liver, spleen, and blood of mice after applying one cycle of cell reprogramming. To achieve this, the researchers have characterized ...

Georgetown University's Lombardi Comprehensive Cancer Center researchers have identified a new way to reprogram T cells, ...

Stem cells hold tremendous potential in healthcare and research science, because they can become any type of cell. However, there were many impediments to using them. They cannot be obtained from ...

Modulation of a single amino acid in the reprogramming factor Kruppel-like factor 4 (KLF4) has been demonstrated to markedly improve natural transcription factor function and to result in faster and ...

Studies on diseases that affect the human brain are usually based on animal models which cannot reproduce the complexity of human neuropathies. Therefore, these methodologies often fail when applied ...

Billions of dollars are pouring into longevity startups as a growing body of research shows that aging might not be as inevitable as we assumed. Now, a startup claims to have reached a major milestone ...

Prostate cancer is one of the most common cancers and the second leading cause of cancer-related death in men worldwide. However, the mechanisms controlling the early stages of prostate cancer ...