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Gastritis is one of the most common findings on an upper endoscopy when someone has GI symptoms. If Helicobacter pylori isn’t present and there’s no clear alcohol-related injury, it often gets labeled as “we’re not totally sure why this is happening” and the default move is to start a proton pump inhibitor (PPI). That can absolutely help, but it’s worth understanding why, and if it’s the right thing to do. Inside the lining of the stomach are tiny nerve sensors called TRPV1 receptors - think of
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